Accumulation of inositol phosphates in human lymphocytes after cholinergic stimulation.

Rapid accumulation and sustained turnover of inositol phosphates in cerebral-cortex slices after muscarinic-receptor stimulation.

The rapid kinetics of [3H]inositol phosphate accumulation and turnover were examined in rat cerebral-cortex slices after muscarinic-receptor stimulation. Markedly increased [3H]inositol polyphosphate concentrations were observed to precede significant stimulated accumulation of [3H]inositol monophosphate. New steady-state accumulations of several 3H-labelled products were achieved after 5-10 mi...

Inositol phosphates in aquatic systems

While there is a considerable body of research on the abundance and behavior of inositol hexakisphosphate in soils, much less is known regarding its behaviour in aquatic systems. The observed physico-chemical behaviour of this organic P species suggests that in marine and freshwaters, it should be complexed and precipitated by major ions such as calcium, magnesium, iron or aluminium, and thus i...

SnapShot: Inositol Phosphates

Stereoselective synthesis of inositol phosphates

Pseudomonas putia'a oxidation of benzene affords cis-3,5-cyclohexadiene1,2diol (JJ which serves as a novel precursor for the syntheses of several natural products including (+)-pinitol, (+)-condunto1 F, D-(-)-myo-inositol 1,4,5-trisphosphate and Dmyo-inositol 1-phosphate. The versatility of this approach is further demonstrated by the preparation of other functionalised cyclitol derivatives, in...

Mutations in genes controlling the biosynthesis and accumulation of inositol phosphates in seeds.

Most of the phosphorus in the resting seed is stored inside protein storage vacuoles as PA (phytic acid; InsP(6)). The biosynthesis and accumulation of PA can be detected beginning from a few days after anthesis and seem to continue during seed development until maturation. The first step in PA biosynthesis is the formation of Ins3P by conversion of glucose 6-phosphate. This is then followed by...